Browsing by Author "Senovilla, Laura"

Now showing items 1-2 of 2

    • The IKK complex contributes to the induction of autophagy 
      Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Helene; Maiuri, M. C.; Morselli, E.; Vitale, I.; Kepp, O.; Tasdemir, E.; Galluzzi, Lorenzo; Shen, S.; Tailler, M.; Delahaye, N.; Tesniere, A.; De Stefano, D.; Ben Younes, Amena; Harper, F.; Pierron, G.; Lavandero González, Sergio; Zitvogel, L.; Israel, A; Baud, V; Kroemer, Guido (NATURE PUBLISHING GROUP, 2010-02-03)
      In response to stress, cells start transcriptional and transcription-independent programs that can lead to adaptation or death. Here, we show that multiple inducers of autophagy, including nutrient depletion, trigger the ...
    • Paradoxical implication of BAX/BAK in the persistence of tetraploid cells 
      Deng, Jiayin; Gutiérrez, Lucía; Stoll, Gautier; Motino, Omar; Martins, Isabelle; Núñez, Lucía; Bravo San Pedro, José Manuel; Humeau, Juliette; Bordenave, Chloe; Pan, Juncheng; Fohrer Ting, Helene; Souquere, Sylvie; Pierron, Gerard; Hetz Flores, Claudio Andres; Villalobos, Carlos; Kroemer, Guido; Senovilla, Laura (Springernature, 2021)
      Pro-apoptotic multi-domain proteins of the BCL2 family such as BAX and BAK are well known for their important role in the induction of mitochondrial outer membrane permeabilization (MOMP), which is the rate-limiting step ...